4kvx

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Template:STRUCTURE 4kvx

Contents

Crystal structure of Naa10 (Ard1) bound to AcCoA

Template:ABSTRACT PUBMED 23912279

Function

[ARD1_SCHPO] Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover (By similarity).

About this Structure

4kvx is a 2 chain structure with sequence from Schizosaccharomyces pombe 972h-. Full crystallographic information is available from OCA.

Reference

  • Liszczak G, Goldberg JM, Foyn H, Petersson EJ, Arnesen T, Marmorstein R. Molecular basis for N-terminal acetylation by the heterodimeric NatA complex. Nat Struct Mol Biol. 2013 Aug 4. doi: 10.1038/nsmb.2636. PMID:23912279 doi:10.1038/nsmb.2636

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