3ps1

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Template:STRUCTURE 3ps1

Contents

Crystal structure of the Escherichia Coli LPXC/LPC-011 complex

Template:ABSTRACT PUBMED 21194954

Function

[D5CV28_ECOKI] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).[HAMAP-Rule:MF_00388][SAAS:SAAS004463_004_013136]

About this Structure

3ps1 is a 1 chain structure with sequence from Escherichia coli ihe3034. Full crystallographic information is available from OCA.

Reference

  • Liang X, Lee CJ, Chen X, Chung HS, Zeng D, Raetz CR, Li Y, Zhou P, Toone EJ. Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold. Bioorg Med Chem. 2011 Jan 15;19(2):852-60. Epub 2010 Dec 9. PMID:21194954 doi:10.1016/j.bmc.2010.12.017

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OCA

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