From Proteopedia
proteopedia link proteopedia link Crystal Structure of Human DOT1L in complex with inhibitor EPZ004777
Structural highlights
4er3 is a 1 chain structure with sequence from Homo sapiens . Full crystallographic information is available from OCA . For a guided tour on the structure components use FirstGlance . Ligands: , , , Related: 4eqz , 4er0 , 4er5 , 4er6 , 4er7 Gene: DOT1L, KIAA1814, KMT4 (Homo sapiens ) Activity: Histone-lysine N-methyltransferase , with EC number 2.1.1.43 Resources: FirstGlance , OCA , RCSB , PDBsum
Categories : Histone-lysine N-methyltransferase Homo sapiens Arrowsmith, C H. Bountra, C. Bradner, J E. Brown, P J. Edwards, A M. Federation, A. Li, Y. Marineau, J. Nguyen, K T. Qi, J. SGC, Structural Genomics Consortium. Schapira, M. Scopton, A. Tempel, W. Vedadi, M. Wernimont, A K. Yu, W. Epigenetic Histone Methyltransferase Transferase-transferase inhibitor complex
