2m17

From Proteopedia

Revision as of 17:54, 19 June 2013 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 2m17

Contents

ubiquitin-like domain-containing C-terminal domain phosphatase (UBLCP1)

Template:ABSTRACT PUBMED 23667555

Function

[UBCP1_HUMAN] Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.[1] [2]

About this Structure

2m17 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Yun JH, Ko S, Lee CK, Cheong HK, Cheong C, Yoon JB, Lee W. Solution Structure and Rpn1 Interaction of the UBL Domain of Human RNA Polymerase II C-Terminal Domain Phosphatase. PLoS One. 2013 May 7;8(5):e62981. doi: 10.1371/journal.pone.0062981. Print 2013. PMID:23667555 doi:10.1371/journal.pone.0062981
  1. ↑ Zheng H, Ji C, Gu S, Shi B, Wang J, Xie Y, Mao Y. Cloning and characterization of a novel RNA polymerase II C-terminal domain phosphatase. Biochem Biophys Res Commun. 2005 Jun 17;331(4):1401-7. PMID:15883030 doi:S0006-291X(05)00831-4
  2. ↑ Guo X, Engel JL, Xiao J, Tagliabracci VS, Wang X, Huang L, Dixon JE. UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc Natl Acad Sci U S A. 2011 Sep 26. PMID:21949367 doi:10.1073/pnas.1113170108

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2m17"
Personal tools