4lcf
From Proteopedia
Contents |
Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-014 complex
Template:ABSTRACT PUBMED 23914798
Function
[LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
About this Structure
4lcf is a 1 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.
Reference
- Liang X, Lee CJ, Zhao J, Toone EJ, Zhou P. Synthesis, structure and antibiotic activity of aryl-substituted LpxC inhibitors. J Med Chem. 2013 Aug 5. PMID:23914798 doi:10.1021/jm4007774
