4jwj

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Template:STRUCTURE 4jwj

Contents

Crystal structure of scTrm10(84)-SAH complex

Template:ABSTRACT PUBMED 24081582

Function

[TRM10_YEAST] Catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNAs.[1] [2]

About this Structure

4jwj is a 2 chain structure with sequence from Baker's yeast. Full crystallographic information is available from OCA.

Reference

  • Shao Z, Yan W, Peng J, Zuo X, Zou Y, Li F, Gong D, Ma R, Wu J, Shi Y, Zhang Z, Teng M, Li X, Gong Q. Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate. Nucleic Acids Res. 2013 Sep 29. PMID:24081582 doi:http://dx.doi.org/10.1093/nar/gkt869
  1. Jackman JE, Montange RK, Malik HS, Phizicky EM. Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9. RNA. 2003 May;9(5):574-85. PMID:12702816
  2. Hiley SL, Jackman J, Babak T, Trochesset M, Morris QD, Phizicky E, Hughes TR. Detection and discovery of RNA modifications using microarrays. Nucleic Acids Res. 2005 Jan 7;33(1):e2. PMID:15640439 doi:http://dx.doi.org/33/1/e2

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