3vtm

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Template:STRUCTURE 3vtm

Contents

Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin

Template:ABSTRACT PUBMED 23649633

Function

[ISDH_STAAM] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity).

About this Structure

3vtm is a 2 chain structure with sequence from Staphylococcus aureus subsp. aureus mu50. Full crystallographic information is available from OCA.

Reference

  • Vu NT, Moriwaki Y, Caaveiro JM, Terada T, Tsutsumi H, Hamachi I, Shimizu K, Tsumoto K. Selective binding of antimicrobial porphyrins to the heme-receptor IsdH-NEAT3 of Staphylococcus aureus. Protein Sci. 2013 Jul;22(7):942-53. doi: 10.1002/pro.2276. Epub 2013 Jun 6. PMID:23649633 doi:10.1002/pro.2276

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