4hzm

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Template:STRUCTURE 4hzm

Contents

Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) bound to N-[(3S,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)piperidin-3-yl]butanamide

Template:ABSTRACT PUBMED 24009110

Function

[NAGZ_SALTY] Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity).

About this Structure

4hzm is a 2 chain structure with sequence from Salty. Full crystallographic information is available from OCA.

See Also

Reference

  • Stubbs KA, Bacik JP, Perley-Robertson GE, Whitworth GE, Gloster TM, Vocadlo DJ, Mark BL. The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to beta-Lactams. Chembiochem. 2013 Oct 11;14(15):1973-81. doi: 10.1002/cbic.201300395. Epub 2013, Sep 5. PMID:24009110 doi:http://dx.doi.org/10.1002/cbic.201300395

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