4bv9

From Proteopedia

Revision as of 11:14, 5 February 2014 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 4bv9

Contents

Crystal structure of the NADPH form of mouse Mu-crystallin.

Template:ABSTRACT PUBMED 24467707

Function

[CRYM_MOUSE] Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity).

About this Structure

4bv9 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Borel F, Hachi I, Palencia A, Gaillard MC, Ferrer JL. Crystal Structure of mouse Mu-crystallin complexed with NADPH and the T3 thyroid hormone. FEBS J. 2014 Jan 27. doi: 10.1111/febs.12726. PMID:24467707 doi:http://dx.doi.org/10.1111/febs.12726

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4bv9"
Personal tools