4js4

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Template:STRUCTURE 4js4

Contents

Crystal structure of E. coli Exonuclease I in complex with a dA16 oligonucleotide

Template:ABSTRACT PUBMED 23609540

Function

[EX1_ECOLI] Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase.

About this Structure

4js4 is a 4 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

  • Korada SK, Johns TD, Smith CE, Jones ND, McCabe KA, Bell CE. Crystal structures of Escherichia coli exonuclease I in complex with single-stranded DNA provide insights into the mechanism of processive digestion. Nucleic Acids Res. 2013 Apr 22. PMID:23609540 doi:10.1093/nar/gkt278

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