2fgt

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Image:2fgt.gif

2fgt, resolution 2.3Å

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Crystal Structure of YycH from Bacillus subtilis

Overview

The Bacillus subtilis YycFG two-component signal transduction system is essential for cell viability, and the YycH protein is part of the regulatory circuit that controls its activity. The crystal structure of YycH was solved by two-wavelength selenium anomalous dispersion data, and was refined using 2.3 A data to an R-factor of 25.2%. The molecule is made up of three domains, and has a novel three-dimensional structure. The N-terminal domain features a calcium binding site and the central domain contains two conserved loop regions.

About this Structure

2FGT is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

The crystal structure of YycH involved in the regulation of the essential YycFG two-component system in Bacillus subtilis reveals a novel tertiary structure., Szurmant H, Zhao H, Mohan MA, Hoch JA, Varughese KI, Protein Sci. 2006 Apr;15(4):929-34. PMID:16600972

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