4khn

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Template:STRUCTURE 4khn

Contents

Crystal structure of the ternary complex of the D714A mutant of RB69 DNA polymerase

Template:ABSTRACT PUBMED 24116139

Function

[DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.

About this Structure

4khn is a 6 chain structure with sequence from Enterobacteria phage rb69. Full crystallographic information is available from OCA.

Reference

  • Jacewicz A, Trzemecka A, Guja KE, Plochocka D, Yakubovskaya E, Bebenek A, Garcia-Diaz M. A Remote Palm Domain Residue of RB69 DNA Polymerase Is Critical for Enzyme Activity and Influences the Conformation of the Active Site. PLoS One. 2013 Oct 7;8(10):e76700. doi: 10.1371/journal.pone.0076700. PMID:24116139 doi:http://dx.doi.org/10.1371/journal.pone.0076700

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