Polarizing CHO hydrogen bonds: The structure of oligonucleotides containing alternating and contiguous tracts of 2'F-RNA and 2'F-ANA nucleotides reveals that nonconventional FCHO hydrogen bonds have a strong stabilizing effect on 2'-fluorinated duplexes.
Backbone FCHO Hydrogen Bonds in 2'F-Substituted Nucleic Acids.,Martin-Pintado N, Deleavey GF, Portella G, Campos-Olivas R, Orozco M, Damha MJ, Gonzalez C Angew Chem Int Ed Engl. 2013 Sep 23. doi: 10.1002/anie.201305710. PMID:24115468[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
↑ Martin-Pintado N, Deleavey GF, Portella G, Campos-Olivas R, Orozco M, Damha MJ, Gonzalez C. Backbone FCHO Hydrogen Bonds in 2'F-Substituted Nucleic Acids. Angew Chem Int Ed Engl. 2013 Sep 23. doi: 10.1002/anie.201305710. PMID:24115468 doi:http://dx.doi.org/10.1002/anie.201305710
