2mj7

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Template:STRUCTURE 2mj7

Contents 1 Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C 2 Disease 3 Function 4 About this Structure

Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C

Disease

[AP4B1_HUMAN] Severe intellectual deficit and progressive spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry.

Function

[AP4B1_HUMAN] Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.

About this Structure

2mj7 is a 1 chain structure. Full experimental information is available from OCA.