4a6c

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Image:4a6c.jpg

Template:STRUCTURE 4a6c

Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors

Template:ABSTRACT PUBMED 22376008

About this Structure

4a6c is a 2 chain structure with sequence from Human immunodeficiency virus. Full crystallographic information is available from OCA.

Reference

  • Wu X, Ohrngren P, Joshi AA, Trejos A, Persson M, Arvela RK, Wallberg H, Vrang L, Rosenquist A, Samuelsson BB, Unge J, Larhed M. Synthesis, X-ray analysis, and biological evaluation of a new class of stereopure lactam-based HIV-1 protease inhibitors. J Med Chem. 2012 Mar 22;55(6):2724-36. Epub 2012 Mar 13. PMID:22376008 doi:10.1021/jm201620t

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OCA

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