4k10

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Template:STRUCTURE 4k10

Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM and Mg2+

Template:ABSTRACT PUBMED 24598749

About this Structure

4k10 is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

Aripirala S, Gonzalez-Pacanowska D, Oldfield E, Kaiser M, Amzel LM, Gabelli SB. Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates. Acta Crystallogr D Biol Crystallogr. 2014 Mar;70(Pt 3):802-10. doi:, 10.1107/S1399004713033221. Epub 2014 Feb 22. PMID:24598749 doi:http://dx.doi.org/10.1107/S1399004713033221

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Categories: Amzel, L M. | Aripirala, S. | Gabelli, S. | Farnesyl diphosphate synthase | Farnesyl pyrophosphate synthase | Fpp | Geranyl transferase | Transferase-transferase inhibitor complex

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