4iy4

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 4iy4

Contents 1 Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4 2 Disease 3 Function 4 About this Structure

Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4

Disease

[CNNM2_HUMAN] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry.

Function

[CNNM2_HUMAN] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity).

About this Structure

4iy4 is a 2 chain structure. Full crystallographic information is available from OCA.