4jbv

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Template:STRUCTURE 4jbv

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1268

Template:ABSTRACT PUBMED 24531197

About this Structure

4jbv is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Vidadala RS, Ojo KK, Johnson SM, Zhang Z, Leonard SE, Mitra A, Choi R, Reid MC, Keyloun KR, Fox AM, Kennedy M, Silver-Brace T, Hume JC, Kappe S, Verlinde CL, Fan E, Merritt EA, Van Voorhis WC, Maly DJ. Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes. Eur J Med Chem. 2014 Mar 3;74:562-73. doi: 10.1016/j.ejmech.2013.12.048. Epub, 2014 Jan 11. PMID:24531197 doi:http://dx.doi.org/10.1016/j.ejmech.2013.12.048

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