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2bps
From Proteopedia
Revision as of 03:09, 30 September 2014 by OCA (Talk | contribs)
2bps is a 2 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The YukD protein in Bacillus subtilis was identified in a hidden Markov model (HMM) search as being related in sequence to ubiquitin. By solving the crystal structure we show that YukD adopts a fold that is most closely related to ubiquitin, yet has the shortest C-terminal tail of all known ubiquitin-like proteins. The endogenous gene of yukD in B. subtilis was disrupted without an obvious phenotypic effect and an inducible copy encoding a C-Myc and His-tagged version of the protein was introduced at the ectopic locus amyE. Conjugation assays performed both in vitro and in vivo indicate that YukD lacks the capacity for covalent bond formation with other proteins.
Crystal structure of the ubiquitin-like protein YukD from Bacillus subtilis.,van den Ent F, Lowe J FEBS Lett. 2005 Jul 4;579(17):3837-41. PMID:15978580[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
↑ van den Ent F, Lowe J. Crystal structure of the ubiquitin-like protein YukD from Bacillus subtilis. FEBS Lett. 2005 Jul 4;579(17):3837-41. PMID:15978580 doi:10.1016/j.febslet.2005.06.002