4j2q
From Proteopedia
Contents |
Crystal structure of C-terminally truncated arrestin reveals mechanism of arrestin activation
Template:ABSTRACT PUBMED 23604253
Disease
[ARRS_BOVIN] Note=S-antigen induces autoimmune uveitis.
Function
[ARRS_BOVIN] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade.
About this Structure
4j2q is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
