From Proteopedia
proteopedia link proteopedia link Solution structure of the WW domain from the human growth-arrest-specific protein 7, GAS-7
Structural highlights
2ysh is a 1 chain structure with sequence from Homo sapiens . Full experimental information is available from OCA . For a guided tour on the structure components use FirstGlance . Gene: GAS7 (Homo sapiens ) Resources: FirstGlance , OCA , RCSB , PDBsum , TOPSAN
Disease
[GAS7_HUMAN ] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.
Function
[GAS7_HUMAN ] May play a role in promoting maturation and morphological differentiation of cerebellar neurons.
Evolutionary Conservation
Check, as determined by ConSurfDB . You may read the explanation of the method and the full data available from ConSurf .
