4l7d
From Proteopedia
Structure of keap1 kelch domain with (1S,2R)-2-{[(1S)-5-methyl-1-[(1-oxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}cyclohexanecarboxylic acid
Template:ABSTRACT PUBMED 24504667
About this Structure
4l7d is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Jnoff E, Albrecht C, Barker JJ, Barker O, Beaumont E, Bromidge S, Brookfield F, Brooks M, Bubert C, Ceska T, Corden V, Dawson G, Duclos S, Fryatt T, Genicot C, Jigorel E, Kwong J, Maghames R, Mushi I, Pike R, Sands ZA, Smith MA, Stimson CC, Courade JP. Binding Mode and Structure-Activity Relationships around Direct Inhibitors of the Nrf2-Keap1 Complex. ChemMedChem. 2014 Feb 6. doi: 10.1002/cmdc.201300525. PMID:24504667 doi:http://dx.doi.org/10.1002/cmdc.201300525
Categories: Human | Albrecht, C. | Barker, J J. | Barker, O. | Beaumont, E. | Bromidge, S. | Brookfield, F. | Brooks, M. | Ceska, T. | Courade, J P. | Crabbe, T. | Duclos, S. | Fryatt, T. | Jigorel, E. | Jnoff, E. | Kwong, J. | Sands, Z. | Smith, M A. | Beta-propeller | Kelch domain | Kelch repeat motif | Nrf2 | Protein-small molecule complex | Stress sensor | Transcription-inhibitor complex
