JMS/Sandbox25

From Proteopedia

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Your Heading Here (maybe something like 'Structure')

spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue. Structural highlights key: w = whale; p = pig; s = seal; c = cat; m = muskrate; g = guniae pig. 8,12,31,53,57,82,84,87,113,116,121,122,132,140. was w53p, c121s and g122m. in every other case removing a hydrophobic patch in each case! , muskrat lost a hydrophic patch but becomes less charged. in blue. in red, is a conserved negatively charge aa - could been both or just increase in charge. p:w 12,53,87,113,116 c:s 8,31,57,82,116,121 g:m 12,82,84,113,122,132 wm 12,113 sm 82

a backbone of 3 myoglobin pairs, oxy and deoxy wt hemoglobin, and deoxy sickle cell, and the horse myoglobin dimer.

showing 1mbn with the sites that have evolved. and hbB from sickle, with the e6v in halo. pymol sequence alignment

References

1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644