Plasminogen

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Plasmin (PLN) is a serine protease which is involved in degradation of fibrin clots. PLN is released as the zymogen plasminogen (PLG) which is converted to the active PLN by a variety of enzymes. PLN cleavage produces angiostatin. PLN domains are: N-terminal, C-terminal serine protease catalytic domain and 5 kringle domains of ca. 80 residues.

3D Structures of plasminogen

Updated on 03-December-2014

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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