Structural highlights
4lk3 is a 6 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , , |
| Gene: | UNQ2538/PRO6079, UXS, UXS1 (HUMAN) |
| Activity: | UDP-glucuronate decarboxylase, with EC number 4.1.1.35 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[UXS1_HUMAN] Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
