Structural highlights
Function
[PROF_PLAFX] Essential for the invasive blood stages of the parasite. Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton. Weakly sequesters actin monomers.[1]
References
- ↑ Kursula I, Kursula P, Ganter M, Panjikar S, Matuschewski K, Schuler H. Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum. Structure. 2008 Nov 12;16(11):1638-48. PMID:19000816 doi:10.1016/j.str.2008.09.008
