| Structural highlights
Function
[FLU_ARATH] Negative regulator of tetrapyrrole biosynthesis (including chlorophyll) in chloroplasts, probably via HEMA1 repression. Inhibits especially the magnesium ion Mg(2+) branch of tetrapyrrole biosynthesis, but independently of heme.[1] [2] [3] [4]
References
- ↑ Meskauskiene R, Nater M, Goslings D, Kessler F, op den Camp R, Apel K. FLU: a negative regulator of chlorophyll biosynthesis in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12826-31. Epub 2001 Oct 16. PMID:11606728 doi:http://dx.doi.org/10.1073/pnas.221252798
- ↑ op den Camp RG, Przybyla D, Ochsenbein C, Laloi C, Kim C, Danon A, Wagner D, Hideg E, Gobel C, Feussner I, Nater M, Apel K. Rapid induction of distinct stress responses after the release of singlet oxygen in Arabidopsis. Plant Cell. 2003 Oct;15(10):2320-32. Epub 2003 Sep 24. PMID:14508004 doi:http://dx.doi.org/10.1105/tpc.014662
- ↑ Goslings D, Meskauskiene R, Kim C, Lee KP, Nater M, Apel K. Concurrent interactions of heme and FLU with Glu tRNA reductase (HEMA1), the target of metabolic feedback inhibition of tetrapyrrole biosynthesis, in dark- and light-grown Arabidopsis plants. Plant J. 2004 Dec;40(6):957-67. PMID:15584960 doi:http://dx.doi.org/10.1111/j.1365-313X.2004.02262.x
- ↑ Przybyla D, Gobel C, Imboden A, Hamberg M, Feussner I, Apel K. Enzymatic, but not non-enzymatic, 1O2-mediated peroxidation of polyunsaturated fatty acids forms part of the EXECUTER1-dependent stress response program in the flu mutant of Arabidopsis thaliana. Plant J. 2008 Apr;54(2):236-48. doi: 10.1111/j.1365-313X.2008.03409.x. Epub 2008 , Jan 7. PMID:18182022 doi:http://dx.doi.org/10.1111/j.1365-313X.2008.03409.x
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