Structural highlights
Publication Abstract from PubMed
The interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1) is a major immunogenic component of schistosomes. It potently triggers the release of interleukin-4 from basophilic granulocytes in an IgE-dependent manner, suggesting a key function in the modulation of the host's immune response to Schistosoma mansoni infection. Here we present the near complete assignment of an IPSE/alpha-1 variant, IPSEDeltaNLS, which comprises the core domain of the protein.
1H, 13C and 15N chemical shift assignments of IPSEDeltaNLS.,Meyer NH, Schramm G, Sattler M Biomol NMR Assign. 2011 Oct;5(2):225-7. doi: 10.1007/s12104-011-9305-6. Epub 2011, Apr 24. PMID:21516468[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Meyer NH, Schramm G, Sattler M. 1H, 13C and 15N chemical shift assignments of IPSEDeltaNLS. Biomol NMR Assign. 2011 Oct;5(2):225-7. doi: 10.1007/s12104-011-9305-6. Epub 2011, Apr 24. PMID:21516468 doi:http://dx.doi.org/10.1007/s12104-011-9305-6
