4z89

Structural highlights

Function

[CAC1A_DROME] Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, neurotransmitter release, gene expression, cell motility, cell division and cell death (By similarity). Probably encodes a dihydropyridine-insensitive current. Vital for survival to adulthood.^{[1] [2]}

References

1. ↑ Smith LA, Wang X, Peixoto AA, Neumann EK, Hall LM, Hall JC. A Drosophila calcium channel alpha1 subunit gene maps to a genetic locus associated with behavioral and visual defects. J Neurosci. 1996 Dec 15;16(24):7868-79. PMID:8987815
2. ↑ Smith LA, Peixoto AA, Kramer EM, Villella A, Hall JC. Courtship and visual defects of cacophony mutants reveal functional complexity of a calcium-channel alpha1 subunit in Drosophila. Genetics. 1998 Jul;149(3):1407-26. PMID:9649530