2jp6

Structural highlights

Function

[KA181_TITCA] Reversible blocker of both Kv1.3/KCNA3 potassium channels of human T-lymphocytes (high affinity) and Shaker B potassium channels (very low affinity).^[1]

See Also

• Potassium channel toxin

References

1. ↑ Batista CV, Gomez-Lagunas F, Rodriguez de la Vega RC, Hajdu P, Panyi G, Gaspar R, Possani LD. Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K(+)-channels with distinctly different affinities. Biochim Biophys Acta. 2002 Dec 16;1601(2):123-31. PMID:12445473