2fiq

Structural highlights

Function

[GATZ_ECOLI] Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of GatY. When expressed alone, GatZ does not show any aldolase activity. Is involved in the catabolism of galactitol.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Nobelmann B, Lengeler JW. Molecular analysis of the gat genes from Escherichia coli and of their roles in galactitol transport and metabolism. J Bacteriol. 1996 Dec;178(23):6790-5. PMID:8955298
2. ↑ Brinkkotter A, Shakeri-Garakani A, Lengeler JW. Two class II D-tagatose-bisphosphate aldolases from enteric bacteria. Arch Microbiol. 2002 May;177(5):410-9. Epub 2002 Mar 16. PMID:11976750 doi:http://dx.doi.org/10.1007/s00203-002-0406-6