This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Beta-2 microglobulin
From Proteopedia
Beta-2 microglobulin (B2M) is a component of MHC class I system. B2M associates with MHC class I α chain, CD1 and Qa. Loss of B2M function causes iron excess. For more details, see: Human beta two microglobulin.
Disease
Elevated B2M levels are found in patients of live cirhossis.
Relevance
B2M is used as a marker for certain types of blood cell cancer. It can indicate the spread and severity of myeloma.
3D Structures of β-2 microglobulin
Updated on 30-November-2015
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Joel L. Sussman, Alexander Berchansky, David Canner
