Dethiobiotin synthetase

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Dethiobiotin synthetase (DTBS) catalyzes the first ring closure in the biotin synthesis. The reaction transforms 7,8-diaminononanoate (DAN), ATP and CO2 to dethiobiotin (DTB), ADP and phosphate.[1]

3D dethiobiotin synthetase

Updated on 24-December-2015

References

  1. ↑ Krell K, Eisenberg MA. The purification and properties of dethiobiotin synthetase. J Biol Chem. 1970 Dec 25;245(24):6558-66. PMID:4921568

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Michal Harel, Alexander Berchansky

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