1brz

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Image:1brz.gif


PDB ID 1brz

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SOLUTION STRUCTURE OF THE SWEET PROTEIN BRAZZEIN, NMR, 43 STRUCTURES


Overview

The fruit of Pentadiplandra brazzeana Baillon contains a small, sweet-tasting protein named brazzein. The structure of brazzein in solution was determined by proton nuclear magnetic resonance spectroscopy at pH 5.2 and 22 degrees C. The brazzein fold, which contains one alpha-helix and three strands of antiparallel beta-sheet, does not resemble that of either of the other two sweet-tasting proteins with known structures, monellin and thaumatin. Instead, the structure of brazzein resembles those of plant gamma-thionins and defensins and arthropod toxins. Sequence comparisons predict that members of a newly-identified family of serine proteinase inhibitors share the brazzein fold.

About this Structure

1BRZ is a Single protein structure of sequence from Pentadiplandra brazzeana. Full crystallographic information is available from OCA.

Reference

Solution structure of the thermostable sweet-tasting protein brazzein., Caldwell JE, Abildgaard F, Dzakula Z, Ming D, Hellekant G, Markley JL, Nat Struct Biol. 1998 Jun;5(6):427-31. PMID:9628478

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