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1eo1
From Proteopedia
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| Domains: | MTH1175 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, JenaLib, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Solution structure of hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum
Overview
The solution structure of MTH1175, a 124-residue protein from the archaeon Methanobacterium thermoautotrophicum has been determined by NMR spectroscopy. MTH1175 is part of a family of conserved hypothetical proteins (COG1433) with unknown functions which contains multiple paralogs from all complete archaeal genomes and the archaeal gene-rich bacterium Thermotoga maritima. Sequence similarity indicates this protein family may be related to the nitrogen fixation proteins NifB and NifX. MTH1175 adopts an alpha/beta topology with a single mixed beta-sheet, and contains two flexible loops and an unstructured C-terminal tail. The fold resembles that of Ribonuclease H and similar proteins, but differs from these in several respects, and is not likely to have a nuclease activity.
About this Structure
1EO1 is a Single protein structure of sequence from Methanothermobacter thermautotrophicus. Full crystallographic information is available from OCA.
Reference
NMR structure determination and structure-based functional characterization of conserved hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum., Cort JR, Yee A, Edwards AM, Arrowsmith CH, Kennedy MA, J Struct Funct Genomics. 2000;1(1):15-25. PMID:12836677
Page seeded by OCA on Wed Mar 26 05:51:58 2008
Categories: Methanothermobacter thermautotrophicus | Single protein | Arrowsmith, C H. | Cort, J R. | Kennedy, M A. | NESG, Northeast Structural Genomics Consortium. | Mixed a/b protein | Mixed beta sheet | Nesg | Northeast structural genomics consortium | Protein structure initiative | Psi | Strand order 321456,strands 2 and 6 antiparallel to rest. | Structural genomic
