Structural highlights
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
Difference electron density maps, based on structure factor amplitudes and experimental phases from crystals of wild-type turnip yellow mosaic virus and those of empty capsids prepared by freeze-thawing, show a large portion of the encapsidated RNA to have an icosahedral distribution. Four unique segments of base-paired, double-helical RNA, one to two turns in length, lie between 33-A and 101-A radius and are organized about either 2-fold or 5-fold icosahedral axes. In addition, single-stranded loops of RNA invade the pentameric and hexameric capsomeres where they contact the interior capsid surface. The remaining RNA, not seen in electron density maps, must serve as connecting links between these secondary structural elements and is likely icosahedrally disordered. The distribution of RNA observed crystallographically appears to be in agreement with models based on biochemical data and secondary structural analyses.
The RNA of turnip yellow mosaic virus exhibits icosahedral order.,Larson SB, Lucas RW, Greenwood A, McPherson A Virology. 2005 Apr 10;334(2):245-54. PMID:15780874[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Larson SB, Lucas RW, Greenwood A, McPherson A. The RNA of turnip yellow mosaic virus exhibits icosahedral order. Virology. 2005 Apr 10;334(2):245-54. PMID:15780874 doi:10.1016/j.virol.2005.01.036
