Structural highlights
Publication Abstract from PubMed
Recent reports suggest that human GII.17 noroviruses are increasing in prevalence. We analyzed the evolutionary changes of three GII.17 capsid protruding (P) domains. We found that the GII.17 P domains had little cross-reactivity with antisera raised against the dominant GII.4 strains. X-ray structural analysis of GII.17 P domains from 2002 to 2014/15 suggested that surface exposed substitutions on the uppermost part of the P domain might have generated a novel 2014/15 GII.17 variant.
Structural evolution of the emerging 2014/15 GII.17 noroviruses.,Singh BK, Koromyslova A, Hefele L, Gurth C, Hansman GS J Virol. 2015 Dec 23. pii: JVI.03119-15. PMID:26699640[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Singh BK, Koromyslova A, Hefele L, Gurth C, Hansman GS. Structural evolution of the emerging 2014/15 GII.17 noroviruses. J Virol. 2015 Dec 23. pii: JVI.03119-15. PMID:26699640 doi:http://dx.doi.org/10.1128/JVI.03119-15
