1e30
From Proteopedia
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CRYSTAL STRUCTURE OF THE MET148GLN MUTANT OF RUSTICYANIN AT 1.5 ANGSTROM RESOLUTION
Overview
The small blue copper protein rusticyanin from Thiobacillus ferrooxidans, contains a type 1 Cu centre with a single axial ligand, Met148, which, together with the His-Cys-His trigonal planar ligands produces a distorted, trigonal pyramidal coordination geometry to copper. Type 1 Cu sites are, found in cupredoxins and several multicopper proteins, including oxidases, and nitrite reductases. The role of the axial ligand has been extensively, debated in terms of its function in the fine tuning of the redox potential, and spectroscopic properties of type 1 Cu sites. Numerous mutations of the, Met ligand in azurins have been studied, but interpretation of the results, has been complicated by the presence of the additional carbonyl oxygen, ligand from Gly45, a neighbouring residue to the ... [(full description)]
About this Structure
1E30 is a [Single protein] structure of sequence from [Acidithiobacillus ferrooxidans] with CU as [ligand]. Structure known Active Sites: CUA and CUB. Full crystallographic information is available from [OCA].
Reference
Structure of the M148Q mutant of rusticyanin at 1.5 A: a model for the copper site of stellacyanin., Hough MA, Hall JF, Kanbi LD, Hasnain SS, Acta Crystallogr D Biol Crystallogr. 2001 Mar;57(Pt 3):355-60. PMID:11223511
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