Sandbox Reserved 433

From Proteopedia

proteopedia linkproteopedia link

This Sandbox is Reserved from January 19, 2016, through August 31, 2016 for use for Proteopedia Team Projects by the class Chemistry 423 Biochemistry for Chemists taught by Lynmarie K Thompson at University of Massachusetts Amherst, USA. This reservation includes Sandbox Reserved 425 through Sandbox Reserved 439.

Contents 1 Estrogen receptor beta/p-hydroxybenzene sulfonamide complexes (2yly)[1] 2 Introduction 3 Overall Structure 4 Binding Interactions 5 Additional Features 6 Quiz Question 1 7 See Also 8 Credits 9 References

Estrogen receptor beta/p-hydroxybenzene sulfonamide complexes (2yly)^[1]

by Benjamin Homyak, Soo Lim Park, Daniel Estabrook, Marissa Burgess, Miranda Goldman

Student Projects for UMass Chemistry 423 Spring 2016

Introduction

spinqualitylabelsall models 2yly, Estrogen Receptor 2 beta/p-hydroxybenzene sulfonamide complexes Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

This is an overall scene with the beta sheets in purple and the alpha helices in ball and stick figures

Here is another scene with a rainbow diagram description of the whole protein

Overall Structure

spinqualitylabelsall models pdbcode, insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

>

Binding Interactions

spinqualitylabelsall models pdbcode, Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Additional Features

spinqualitylabelsall models pdbcode, Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Quiz Question 1

spinqualitylabelsall models pdbcode, Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

See Also

• [Estrogen Receptor]
• [1yy4]
• [1u3s]
• [1x78]
• [1qkn]

Credits

Introduction - Miranda Goldman

Overall Structure - Marissa Burgess

Drug Binding Site - Soo Lim Park

Additional Features - Benjamin Homyak

Quiz Question 1 - Daniel Estabrook

References

1. ↑ Roberts LR, Armor D, Barker C, Bent A, Bess K, Brown A, Favor DA, Ellis D, Irving SL, MacKenny M, Phillips C, Pullen N, Stennett A, Strand L, Styles M. Sulfonamides as selective oestrogen receptor beta agonists. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5680-3. Epub 2011 Aug 16. PMID:21885279 doi:10.1016/j.bmcl.2011.08.041