2j8m

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2j8m, resolution 1.44Å

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STRUCTURE OF P. AERUGINOSA ACETYLTRANSFERASE PA4866

Overview

The gene PA4866 from Pseudomonas aeruginosa is documented in the, Pseudomonas genome database as encoding a 172 amino acid hypothetical, acetyltransferase. We and others have described the 3D structure of this, protein (termed pita) [Davies et al. (2005) Proteins: Struct., Funct., Bioinf. 61, 677-679; Nocek et al., unpublished results], and structures, have also been reported for homologues from Agrobacterium tumefaciens, (Rajashankar et al., unpublished results) and Bacillus subtilis [Badger et, al. (2005) Proteins: Struct., Funct., Bioinf. 60, 787-796]. Pita, homologues are found in a large number of bacterial genomes, and while the, majority of these have been assigned putative phosphinothricin, acetyltransferase activity, their true function is unknown. In this paper, we report that ... [(full description)]

About this Structure

2J8M is a [Single protein] structure of sequence from [Pseudomonas aeruginosa] with AZI, SO4 and GOL as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

l-Methionine sulfoximine, but not phosphinothricin, is a substrate for an acetyltransferase (gene PA4866) from Pseudomonas aeruginosa: structural and functional studies., Davies AM, Tata R, Beavil RL, Sutton BJ, Brown PR, Biochemistry. 2007 Feb 20;46(7):1829-39. Epub 2007 Jan 25. PMID:17253769

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