Alpha-lactalbumin

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Contents 1 Function 2 Relevance 3 3D Structures of lactalbumin 4 References

Function

Lactalbumin (LCA) is the albumin contained in milk and obtained from whey. It has α (LCAa)^[1] and β (LCAb) forms. LCAa is the regulatory subunit of the lactose synthase heterodimer which produces lactose by transferring galactose moieties to glucose.

Relevance

LCAa is tested as a target for potential breast cancer vaccine. LCAb is the major whey protein of cow and sheep milk. LCAb is the target of testing for the presence of milk as an allergen.

3D Structures of lactalbumin

Updated on 07-April-2016

References

1. ↑ Permyakov EA, Berliner LJ. alpha-Lactalbumin: structure and function. FEBS Lett. 2000 May 19;473(3):269-74. PMID:10818224