Leukocyte-associated immunoglobulin-like receptor

Leukocyte-associated immunoglobulin-like receptors (LAIR-1) is an immunoreceptor tyrosine-based inhibitory motif-bearing receptor expressed in the majority of peripheral mononuclear cells like T cells, B cells and NK cells ^[1].

3D structures of leukocyte-associated immunoglobulin-like receptor

Updated on 11-April-2016

• • 3kgr, 3rp1 – hLAIR-1 ectodomain - human
    
  • 4esk, 4ety – LAIR-1 ectodomain - mouse
    

References

1. ↑ van der Vuurst de Vries AR, Clevers H, Logtenberg T, Meyaard L. Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is differentially expressed during human B cell differentiation and inhibits B cell receptor-mediated signaling. Eur J Immunol. 1999 Oct;29(10):3160-7. PMID:10540327