Function
Menin (Men) is a putative tumor suppressor. Men possesses two functional nuclear localization signals and inhibits transcriptional activation by JunD.
Disease
Relevance
Structural highlights
3D structures of menin
Updated on 05-May-2015
3u84 – hMen – human
4og3, 4og4, 4og5, 4og6, 4og7, 4og8 – hMen + inhibitor
4gpq, 4gq3, 4gq4, 4x5y, 4x5z – hMen (mutant) + inhibitor
4i80 – hMen + peptide inhibitor
3u85 – hMen + histone-lysine N-methyltransferase Mll peptide
4gq6 – hMen (mutant) + histone-lysine N-methyltransferase Mll peptide
3u86 – hMen + JunD peptide
3u88 – hMen + histone-lysine N-methyltransferase Mll + lens epithelium-derived growth factor
References
