Phosphotriesterase

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Phosphotriesterase or aryldialkylphosphatase (PTE) catalyzes the conversion of aryl dialkyl phosphate to dialkyl phosphate and aryl alcohol. PTE has no known natural substrate but has potential in detoxification of organophosphates poisons lethal effects. PTE can detoxify the insecticide paraoxon and the chemical warfare agent sarin.

3D structures of phosphotriesterase

Updated on 13-May-2015

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Michal Harel, Joel L. Sussman, Alexander Berchansky

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