Plasminogen activator inhibitor

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Plasminogen activator inhibitor (PAI) is a serine protease inhibitor.

  • PAI-1 inhibits tissue plasminogen activator and urokinase[1].
  • PAI-2 is secreted by the placenta and is present during pregnancy.
  • PAI-3 inhibits enzymes in blood coagulation.

3D Structures of plasminogen activator inhibitor

Updated on 05-July-2016

References

  1. ↑ Lijnen HR. Pleiotropic functions of plasminogen activator inhibitor-1. J Thromb Haemost. 2005 Jan;3(1):35-45. PMID:15634264 doi:http://dx.doi.org/10.1111/j.1538-7836.2004.00827.x

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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