1jy5

From Proteopedia

Revision as of 10:10, 20 March 2008 by OCA (Talk | contribs)
Jump to: navigation, search
Image:1jy5.gif


PDB ID 1jy5

Drag the structure with the mouse to rotate
, resolution 2.05Å
Coordinates: save as pdb, mmCIF, xml



RNase-related protein from Calystegia sepium


Overview

The structure of a catalytically inactive RNase-related protein from Calystegia sepium (CalsepRRP) has been resolved by protein crystallography at a resolution of 2.05 A and an R factor of 20.74%. Although the protein is completely devoid of ribonuclease activity, it adopts the typical alpha + beta structure of non-base-specific RNases. Analysis of the structure revealed that two amino-acid substitutions in the 'active' P1 site, in combination with the less hydrophobic/aromatic character of the B1 base-recognition site and a completely disrupted B2 base-recognition site, might account for this complete lack of activity.

About this Structure

1JY5 is a Single protein structure of sequence from Calystegia sepium. Full crystallographic information is available from OCA.

Reference

Structure of an RNase-related protein from Calystegia sepium., Rabijns A, Verboven C, Rouge P, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):627-33. Epub 2002, Mar 22. PMID:11914487

Page seeded by OCA on Thu Mar 20 12:10:02 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1jy5"
Personal tools