1k83
From Proteopedia
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| , resolution 2.80Å | |||||||
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| Ligands: | and | ||||||
| Activity: | DNA-directed RNA polymerase, with EC number 2.7.7.6 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of Yeast RNA Polymerase II Complexed with the Inhibitor Alpha Amanitin
Overview
The structure of RNA polymerase II in a complex with the inhibitor alpha-amanitin has been determined by x-ray crystallography. The structure of the complex indicates the likely basis of inhibition and gives unexpected insight into the transcription mechanism.
About this Structure
1K83 is a Protein complex structure of sequences from Amanita phalloides and Saccharomyces cerevisiae. The following page contains interesting information on the relation of 1K83 with [RNA Polymerase]. Full crystallographic information is available from OCA.
Reference
Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution., Bushnell DA, Cramer P, Kornberg RD, Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1218-22. Epub 2002 Jan 22. PMID:11805306
Page seeded by OCA on Thu Mar 20 12:13:47 2008
