Pyridoxine 5'-phosphate oxidase
From Proteopedia
Pyridoxine 5’-phosphate oxidase (PPO) catalyzes the oxidation of pyridoxamine-phosphate by molecular oxygen producing pyridoxal 5’-phosphate, ammonia and hydrogen peroxide. pyridoxal 5’-phosphate (PLP), commonly known as vitamin B6, which is a biological essential cofactor. PPO catalyzes the last step in vitamin B6 metabolism. PPO uses FMN as cofactor.
3D structures of pyridoxine 5'-phosphate oxidase
1dnl, 1g76, 1wv4 – EcPPO – Escherichia coli
1g76, 1g77, 1g78, 1g79, 1jnw – EcPPO + PLP
1nrg - hPPO + PLP – human
3hy8 - hPPO (mutant) + PLP
2aq6 - PPO + PLP – Mycobacterium tuberculosis
