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4msp

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Template:STRUCTURE 4msp

Contents

Crystal structure of human peptidyl-prolyl cis-trans isomerase FKBP22 (aka FKBP14) containing two EF-hand motifs

Template:ABSTRACT PUBMED 24272907

Disease

[FKB14_HUMAN] Ehlers-Danlos syndrome, kyphoscoliotic and deafness type. The disease is caused by mutations affecting the gene represented in this entry.

Function

[FKB14_HUMAN] PPIases accelerate the folding of proteins during protein synthesis.

About this Structure

4msp is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Boudko SP, Ishikawa Y, Nix J, Chapman MS, Bachinger HP. Structure of human peptidyl-prolyl cis-trans isomerase FKBP22 containing two EF-hand motifs. Protein Sci. 2014 Jan;23(1):67-75. doi: 10.1002/pro.2391. Epub 2013 Nov 25. PMID:24272907 doi:http://dx.doi.org/10.1002/pro.2391

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OCA

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