2fe1

Structural highlights

Function

[Q8ZZP3_PYRAE] Toxic component of a toxin-antitoxin (TA) module. Has ribonuclease activity.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Pandey DP, Gerdes K. Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes. Nucleic Acids Res. 2005 Feb 17;33(3):966-76. Print 2005. PMID:15718296 doi:http://dx.doi.org/10.1093/nar/gki201
2. ↑ McKenzie JL, Duyvestyn JM, Smith T, Bendak K, Mackay J, Cursons R, Cook GM, Arcus VL. Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry. RNA. 2012 Jun;18(6):1267-78. doi: 10.1261/rna.031229.111. Epub 2012 Apr 26. PMID:22539524 doi:http://dx.doi.org/10.1261/rna.031229.111